Article
Influence of mutation in human apolipoprotein A-1 gene promoter on plasma LDL cholesterol response to dietary fat.
Lancet (London, England) - 21 May 1994
Lopez-Miranda J, Ordovas J M, Espino A, Marin C, Salas J, Lopez-Segura F, Jimenez-Pereperez J, Perez-Jimenez F
Abstract excerpt
The plasma lipid response to changes in dietary fat and cholesterol can vary between individuals. At present, responders cannot be identified in advance. An adenine to guanine (A-->G) mutation in the promoter of the apolipoprotein A1 gene (apoA-1) has been suggested as affecting plasma high-densi...
Topics
- Adult
- Alleles
- Apolipoprotein A-I
- Base Sequence
- Cholesterol, Dietary
- Cholesterol, LDL
- DNA Primers
- Dietary Fats
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Phenotype
- Promoter Regions, Genetic