Article
Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma.
Biomolecules - 8 May 2023
Konjevod Marcela, Sreter Katherina B, Popovic-Grle Sanja, Lampalo Marina, Tudor Lucija, Jukic Irena, Nedic Erjavec Gordana, Bingulac-Popovic Jasna, Safic Stanic Hana, Nikolac Perkovic Matea, Markeljevic Jasenka, Samarzija Miroslav, Pivac Nela, Svob Strac Dubravka
Abstract excerpt
The complex role of the serotonin system in respiratory function and inflammatory diseases such as asthma is unclear. Our study investigated platelet serotonin (5-HT) levels and platelet monoamine oxidase B (MAO-B) activity, as well as associations with HTR2A (rs6314; rs6313), HTR2C (rs3813929; rs518147), and MAOB (rs1799836; ) gene polymorphisms in 120 healthy individuals and 120 asthma patients of...
