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Article

A Caenorhabditis elegans RNA-directed RNA polymerase in sperm development and endogenous RNA interference.

Genetics - 1 Dec 2009

Gent Jonathan I, Schvarzstein Mara, Villeneuve Anne M, Gu Sam Guoping, Jantsch Verena, Fire Andrew Z, Baudrimont Antoine

Abstract excerpt

Short interfering RNAs (siRNAs) are a class of regulatory effectors that enforce gene silencing through formation of RNA duplexes. Although progress has been made in identifying the capabilities of siRNAs in silencing foreign RNA and transposable elements, siRNA functions in endogenous gene regulation have remained mysterious. In certain organisms, siRNA biosynthesis involves novel enzymes that act as...

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Identifiers

PMID: 19805814
DOI: 10.1534/genetics.109.109686
PMCID: PMC2787422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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