Article
Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.
Archives of general psychiatry - 1 Oct 2009
Donohoe Gary, Walters James, Morris Derek W, Quinn Emma M, Judge Róisín, Norton Nadine, Giegling Ina, Hartmann Annette M, Möller Hans-Jürgen, Muglia Pierandrea, Williams Hywel, Moskvina Valentina, Peel Rosemary, O'Donoghue Therese, Owen Michael J, O'Donovan Michael C, Gill Michael, Rujescu Dan, Corvin Aiden
Abstract excerpt
CONTEXT: Human and animal studies have implicated the gene NOS1 in both cognition and schizophrenia susceptibility. OBJECTIVE: To investigate whether a potential schizophrenia risk single-nucleotide polymorphism (rs6490121) identified in a recent genome-wide association study negatively influences cognition in patients with schizophrenia and healthy control subjects. DESIGN: A comparison of both cases and...
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