Article
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Chandler David, Dragović Milan, Cooper Matthew, Badcock Johanna C, Mullin Benjamin H, Faulkner Deb, Wilson Scott G, Hallmayer Joachim, Howell Sarah, Rock Daniel, Palmer Lyle J, Kalaydjieva Luba, Jablensky Assen
Abstract excerpt
Neuritin 1 (NRN1), an activity-regulated gene with multiple roles in neurodevelopment and synaptic plasticity, is located within the 6p24-p25 interval on chromosome 6, previously identified as linked to a subtype of schizophrenia (SZ) characterized by pervasive cognitive deficit (CD). We have tested the effect of NRN1 sequence variation on susceptibility to SZ and on general cognitive ability in patients and...
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