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Article

Clinical trials of agents that reverse multidrug resistance. A literature review.

Cancer - 15 Dec 1993

Raderer M, Scheithauer W

Abstract excerpt

BACKGROUND: The discovery of the P-170 glycoprotein as a mediator of multidrug resistance (MDR) represents one of the most important research accomplishments in antineoplastic pharmacology during the last decade. Demonstration of P-170 in epithelial tissues, untreated and chemotherapeutically pretreated human malignancies, and identification of various agents capable of reversing resistance in vitro generated...

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PMID: 8252468
DOI: 10.1002/1097-0142(19931215)72:12<3553::aid-cncr2820721203>3.0.co;2-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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