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Article

Clinical relevance of immunocytochemical detection of multidrug-resistance-associated P-glycoprotein in hematologic malignancies.

Tumori - 31 Aug 1990

Musto P, Cascavilla N, Di Renzo N, Ladogana S, La Sala A, Melillo L, Nobile M, Matera R, Lombardi G, Carotenuto M

Abstract excerpt

P-glycoprotein (P-170) is the phenotypic marker of tumoral cells that show the phenomenon of multidrug resistance (MDR). Using an immunocytochemical approach, we employed the monoclonal antibody C219 (which recognizes an epitope of such a glycoprotein) to evaluate in cytologic samples the express...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Antineoplastic Agents
Drug Resistance
Humans
Immunohistochemistry
Leukemia
Longitudinal Studies
Membrane Glycoproteins
Phenotype
Predictive Value of Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1975959
DOI: 10.1177/030089169007600410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1975959-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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