Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes.

doi:10.1101/gad.4.11.1925

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Article

Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes.

Genes & development - 1 Nov 1990

Brown B D, Harland R M

Abstract excerpt

We have identified a messenger RNA (mRNA) sequence from a Xenopus homeo box-containing gene that is the target for a sequence-specific endoribonuclease in vivo. Synthetic RNA transcribed from an allele of the maternal gene Xlhbox2B is efficiently cleaved when injected into Xenopus oocytes. The cleavage sequence lies between the protein-coding region and a 600-base 3'-untranslated region. Intermediates in...

Topics

Alleles
Animals
Base Sequence
Blotting, Northern
Cloning, Molecular
Endoribonucleases
Female
Genes, Homeobox
In Vitro Techniques
Molecular Sequence Data
Oligonucleotide Probes
Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Antisense

RNA, Messenger

Repetitive Sequences, Nucleic Acid

Templates, Genetic

Transcription, Genetic

Xenopus

Source

Open in PubMed

Identifiers

PMID: 1980477
DOI: 10.1101/gad.4.11.1925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1980477-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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