Article
Determination of an RNA structure involved in splicing inhibition of a muscle-specific exon.
Journal of molecular biology - 5 Oct 1991
Clouet d'Orval B, d'Aubenton-Carafa Y, Brody J M, Brody E
Abstract excerpt
We have investigated the RNA structure of the region surrounding the muscle-specific exon 6B of the chicken beta-tropomyosin gene. We have used a variety of chemical and enzymatic probes: dimethylsulfate, N-cyclohexyl-N'-(2-(N-methylmorpholino)-ethyl)-carbodiimide-p-tolu enesulfonate) , RNase T1 and RNase V1. Lead acetate was also used to obtain some information on the tertiary structure of this region. Probing...
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