Article
Analysis of the interaction of the nucleotide base with myosin and the effect on substrate efficacy.
Biophysical journal - 7 Oct 2009
Hyatt David, Cooke Roger, Pate Edward
Abstract excerpt
A wide variety of purine- and pyrimidine-based nucleotides can serve as a substrate for actomyosin mechanics, but with varying effectiveness. To understand the myosin-ATP interaction and in particular, the interactions with the base, we have used molecular dynamics simulations to model the intera...
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