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Article

X Chromosome inactivation pattern is not associated with interindividual variations in thyroid volume: a study of euthyroid Danish female twins.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Oct 2009

Brix Thomas Heiberg, Hansen Pia Skov, Bennedbak Finn Noe, Bonnema Steen Joop, Kyvik Kirsten Ohm, Ørstavik Karen Helene, Hegedüs Laszlo

Abstract excerpt

Ahigher frequency of skewed X chromosome inactivation (XCI) is found in patients with autoimmune thyroid disease (AITD) than in controls. Although goitre is often present in AITD, a recent study failed to show an association between XCI and clinically overt nontoxic goitre. However, the etiology of overt goitre is complex, and the mechanisms influencing thyroid volume may involve fewer factors than the mechanisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19803777
DOI: 10.1375/twin.12.5.502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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