Article
Twins as a tool for evaluating the influence of genetic susceptibility in thyroid autoimmunity.
Annales d'endocrinologie - 1 Apr 2011
Brix T H, Hegedüs L
Abstract excerpt
By means of large twin cohorts, it has been possible to provide relatively valid and unbiased data regarding the influence of genetic and to some extent epigenetic factors in the aetiology of thyroid autoimmunity. The comparison of concordance rates between monozygotic and dizygotic twins provides irrefutable evidence of a genetic component in the aetiology of both Graves' disease and Hashimoto's thyroiditis, as...
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