Article
Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1.
Human molecular genetics - 1 Oct 1997
Stöger R, Kajimura T M, Brown W T, Laird C D
Abstract excerpt
Genomic methylation patterns of mammals can vary among individuals and are subject to dynamic changes during development. In order to gain a better understanding of this variation, we have analyzed patterns of cytosine methylation within a 200 bp region at the CpG island of the human FMR1 gene from leukocyte DNA. FMR1 is normally methylated during inactivation of the X chromosome in females and it is also...
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