Article
[A quantitative assay for JAK2 mutation in 135 patients with chronic myeloproliferative neoplasms].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2009
Chao Hong-ying, Shen Yi-min, Zhang Ri, Feng Yu-feng, Cen Jian-nong, Yao Li, Shen Hong-jie, Zhu Zi-ling, Xue Yong-quan
Abstract excerpt
OBJECTIVE: To investigate the frequency and mutational status of JAK2 mutation in Chinese patients with chronic myeloproliferative neoplasms (MPN) and study the relative quantitation and clinical implications of mutated JAK2 transcript. METHODS: JAK2 mutation and the mutational status were screened with amplification-refractory mutation sequencing polymerase chain reaction (ARMS-PCR), the relative quantity of...
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