Article
Quantitative assay for Janus kinase 2 (JAK2) mutation in Chinese patients with chronic myeloproliferative disorders.
The Journal of international medical research - 1 Jan 2000
Shen Y-M, Chao H-Y, Zhang R, Feng Y-F, Cen J-N, Yao L, Shen H-J, Zhu Z-L, Xue Y-Q
Abstract excerpt
The Janus kinase 2 (JAK2) V617F mutation has considerably helped understanding of the molecular pathogenesis of chronic myeloproliferative disorders (MPD), hence this study investigated for the first time the mutational status and relative quantitation of JAK2 V617F mRNA in Chinese patients with chronic MPD. The study cohort comprised 123 chronic MPD patients (35 with polycythaemia vera [PV], 85 with essential...
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