Article
[Quantitative analysis for JAK2 mutation in 98 patients with essential thrombocythemia and its clinical significance].
Zhongguo shi yan xue ye xue za zhi - 1 Jun 2009
Chao Hong-Ying, Shen Yi-Min, Zhang Ri, Feng Yu-Feng, Cen Jian-Nong, Yao Li, Shen Hong-Jie, Zhu Zi-Ling, Xue Yong-Quan
Abstract excerpt
The objective of this study was to identify the frequency and types of JAK2V617F mutation in chinese patients with essential thrombocythemia (ET), to quantitatively detect the level of mutation transcripts and to investigate its clinical significance. The frequency and types of JAK2V617F mutation were detected by amplification-refractory mutation sequencing polymerase chain reaction (ARMS-PCR), the transcript...
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