Article
[The clinical implication of JAK2 mutation expression in patients with myeloproliferative disorders].
Zhonghua nei ke za zhi - 1 Apr 2007
Fei Hai-rong, Zhang Ri, Chen Su-ning, Pan Jin-lan, Cen Jian-nong, Xue Yong-quan
Abstract excerpt
OBJECTIVE: To investigate the frequency and clinical implication of JAK2V617F mutation in Chinese patients with myeloproliferative disorders (MPD). METHODS: Genomic DNA from bone marrow or blood mononuclear cells of 137 cases of MPD was screened with allele-specific polymerase chain reaction (PCR) and JAK2V617F mutation was detected with gel electrophoresis. There were 57 cases with polycythemia vera (PV), 68...
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