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Article

Monoclonal antibody specific for IDH1 R132H mutation.

Acta neuropathologica - 1 Nov 2009

Capper David, Zentgraf Hanswalter, Balss Jörg, Hartmann Christian, von Deimling Andreas

Abstract excerpt

IDH1 R132H mutations occur in approximately 70% of astrocytomas and oligodendroglial tumors. We developed a mouse monoclonal antibody targeting the IDH1 R132H mutation. Here, we show the high specificity and sensitivity of this antibody on Western blots and tissue sections from formalin fixed paraffin embedded tumor specimens. This antibody is highly useful for tumor classification, in detecting single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19798509
DOI: 10.1007/s00401-009-0595-z

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Monoclonal antibody specific for IDH1 R132H mutation.PMID 19798509Read ↗

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