Article
Immunogenetics of rheumatoid arthritis and juvenile arthritis.
Recenti progressi in medicina - 1 Jan 2000
Stastny P, Gao X J, Fernandez-Viña M
Abstract excerpt
Starting with the historical background and ending with the most recent data obtained by DNA typing, using PCR and oligonucleotide probes, the role of HLA antigens in rheumatoid arthritis (RA) and in several forms of juvenile arthritis (JA) is reviewed. RA is thought to be associated with an epitope of the third hypervariable region of DRB1 which is shared by several alleles including DR4-Dw4, Dw14, Dw15, DR1,...
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