Article
[Occurrence of GRB10 (+11275G > A) polymorphism in Hungarian population and its relationship to glucose metabolism].
Orvosi hetilap - 4 Oct 2009
Vitai Márta, Buday Barbara, Kulcsár Eniko, Literáti-Nagy Botond, Vecsei Istvánné, Bezzegh Katalin, Péterfai Eva, Kurucz István, Korányi László
Abstract excerpt
In our backstage experiment with differential display method among the differentially expressed genes we found the gene of GRB10 (Growth factor Receptor-Bound protein 10). The GRB10 protein binds to insulin and insulin-like growth factor receptors and acts as a negative regulatory protein. Besides, GRB10 gene polymorphisms are connected to the development of type 2 diabetes mellitus. In this experiment we...
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