Article
Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.
The New England journal of medicine - 7 Jan 1993
Groop L C, Kankuri M, Schalin-Jäntti C, Ekstrand A, Nikula-Ijäs P, Widén E, Kuismanen E, Eriksson J, Franssila-Kallunki A, Saloranta C
Abstract excerpt
BACKGROUND: The storage of glucose as glycogen in skeletal muscle is frequently impaired in patients with non-insulin-dependent diabetes mellitus (NIDDM) and their nondiabetic relatives. Despite an intensive search for candidate genes associated with NIDDM, no data have been available on the gene...
Topics
- Alleles
- Blood Glucose
- Chi-Square Distribution
- DNA Probes
- Diabetes Mellitus, Type 2
- Female
- Glycogen Synthase
- Humans
- Insulin Resistance
- Male
- Middle Aged
- Muscles
- Polymorphism, Genetic