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MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease.

Blood - 10 Dec 2009

Boukouaci Wahid, Busson Marc, Peffault de Latour Régis, Rocha Vanderson, Suberbielle Caroline, Bengoufa Djaouida, Dulphy Nicolas, Haas Philippe, Scieux Catherine, Amroun Habiba, Gluckman Eliane, Krishnamoorthy Rajagopal, Toubert Antoine, Charron Dominique, Socié Gérard, Tamouza Ryad

Abstract excerpt

The MHC class I-related chain A (MICA) molecules exist as membrane-bound and soluble isoforms and are encoded by a polymorphic gene. Their genetic and phenotype characteristics have been studied in various pathologic settings but not in the context of hematopoietic stem cell transplantation (HSCT). Here, we evaluated whether MICA-related features namely MICA-129 gene polymorphism, serum levels of soluble MICA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19786616
DOI: 10.1182/blood-2009-04-217430

Genes

MICA

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MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease.PMID 19786616Read ↗

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