Article
MICA gene polymorphism in kidney allografts and possible impact of functionally relevant variants.
Transplantation proceedings - 1 Dec 2010
Tonnerre P, Gérard N, Chatelais M, Charreau B
Abstract excerpt
It is likely that the polymorphic MICA (MHC class I related chain A) molecules on graft endothelial cells (ECs) may be a target for specific antibodies and T cells directed against solid organ grafts. Although there is evidence for a role of MICA in vascular and transplant biology, genotyping is not performed routinely, and thus there are few correlations between polymorphism and endothelial phenotype. The...
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