Article
MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.
Frontiers in immunology - 1 Jan 2018
Zingoni Alessandra, Vulpis Elisabetta, Cecere Francesca, Amendola Maria G, Fuerst Daniel, Saribekyan Taron, Achour Adnane, Sandalova Tatyana, Nardone Ilaria, Peri Agnese, Soriani Alessandra, Fionda Cinzia, Mariggiò Elena, Petrucci Maria T, Ricciardi Maria R, Mytilineos Joannis, Cippitelli Marco, Cerboni Cristina, Santoni Angela
Abstract excerpt
Natural killer (NK) cells are immune innate effectors playing a pivotal role in the immunosurveillance of multiple myeloma (MM) since they are able to directly recognize and kill MM cells. In this regard, among activating receptors expressed by NK cells, NKG2D represents an important receptor for the recognition of MM cells, being its ligands expressed by tumor cells, and being able to trigger NK cell...
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