Use of fetal intestinal isografts from normal and transgenic mice to study the programming of positional information along the duodenal-to-colonic axis.

Abstract excerpt

The four principal cellular constituents of the mouse intestinal epithelium are all derived from a multipotent stem cell functionally anchored near the base of its crypts. Differentiation of enterocytes, enteroendocrine, and goblet cells occurs during an orderly upward migration from monoclonal crypts supplied by a single active stem cell to adjacent polyclonal small intestinal villi or to their colonic homologs,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Digestive system and related health
• Share to Infant Nutrition and Health
• Share to Pediatric Hepatobiliary Diseases and Treatments