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Article

Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease.

Experimental neurology - 1 Jun 2010

Folwell James, Cowan Catherine M, Ubhi Kiren K, Shiabh Hassan, Newman Tracey A, Shepherd David, Mudher Amritpal

Abstract excerpt

Alzheimer's disease (AD) is characterised by neurofibrillary tangles composed of hyper-phosphorylated tau, and neuritic plaques composed of misfolded amyloid peptide (Abeta(42)). It is generally believed that the hyper-phosphorylated tau and oligomeric Abeta(42) are responsible for the neuronal d...

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Identifiers

PMID: 19782075
DOI: 10.1016/j.expneurol.2009.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19782075-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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