Article
Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila.
Genetics - 1 Mar 2008
Cao Weihuan, Song Ho-Juhn, Gangi Tina, Kelkar Anju, Antani Isha, Garza Dan, Konsolaki Mary
Abstract excerpt
Sustained increases in life expectancy have underscored the importance of managing diseases with a high incidence in late life, such as various neurodegenerative conditions. Alzheimer's disease (AD) is the most common among these, and consequently significant research effort is spent on studying it. Although a lot is known about the pathology of AD and the role of beta-amyloid (Abeta) peptides, the complete...
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