Article
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
Molecular brain - 25 Sept 2009
Lu Yubing, Ferris Jacob, Gao Fen-Biao
Abstract excerpt
BACKGROUND: TDP-43 is an evolutionarily conserved RNA-binding protein implicated in the pathogenesis of frontotemporal dementia (FTD), sporadic and familial amyotrophic lateral sclerosis (ALS), and possibly other neurodegenerative diseases. In diseased neurons, TDP-43 is depleted in the nucleus,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
