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Article

Molecular clones of SIVsm and SIVagm: experimental infection of macaques and African green monkeys.

Journal of medical primatology - 1 Jan 1990

Johnson P R, Goldstein S, London W T, Fomsgaard A, Hirsch V M

Abstract excerpt

We have investigated the ability of biologically-active proviral molecular clones of SIVsm and SIVagm to infect rhesus macaques, pig-tail macaques, and African green monkeys. Two clones of SIVsm were individually inoculated into four rhesus and four pig-tail macaques. All eight macaques became infected, and two have experienced a significant decline in absolute numbers of circulating CD4+ cells. None of three...

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Identifiers

PMID: 1977919

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