Article
Breast cancer and cyclin D1 gene polymorphism in Turkish women.
In vivo (Athens, Greece) - 1 Jan 2000
Yaylim-Eraltan Ilhan, Ergen Arzu, Görmüs Uzay, Arikan Soykan, Küçücük Seden, Sahin Orhan, Yigit Nilüfer, Yildiz Yemliha, Isbir Turgay
Abstract excerpt
BACKGROUND: Cyclin D1 protein plays an important part in regulating the progress of the cell during the G(1) phase of the cell cycle. It has been suggested that G870A polymorphism at the exon4/intron4 splicing region of the CCND1 gene may play a role in tumorigenesis and invasiveness. PATIENTS AND METHODS: A case-control study was performed to test the association between G870A polymorphisms in the CCND1 gene and...
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