Article
The influence of cyclin D1 A870G polymorphism on colorectal cancer risk and prognosis in a Turkish population.
Anticancer research - 1 Jul 2010
Yaylim-Eraltan Ilhan, Arikan Soykan, Yildiz Yemliha, Cacina Canan, Ergen H Arzu, Tuna Gulay, Görmüs Uzay, Zeybek Umit, Isbir Turgay
Abstract excerpt
BACKGROUND: Cyclin D1, encoded by the gene CCND1, is a regulatory protein in the cell cycle transition from G(1) phase to S phase. A common polymorphism (A870G) at codon 242 affects splicing of the CCND1 transcript and may cause uncontrollable cellular growth. The present study was performed to t...
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