Article
Association between IRF-5 polymorphisms and risk of acute coronary syndrome.
DNA and cell biology - 1 Jan 2010
Fan Jing-Han, Gao Lin-Bo, Pan Xin-Min, Li Cui, Liang Wei-Bo, Liu Jin, Li Yi, Zhang Lin
Abstract excerpt
Previous studies suggested that genetic polymorphisms in interferon regulatory factor 5 (IRF-5) are implicated in the susceptibility to a range of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease. Recently, IRF-5 has been implicated in inflammatory processes that are associated with excessive remodeling and atherosclerosis. Our purpose was to...
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