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Article

Molecular genetic study on GATA5 gene promoter in acute myocardial infarction.

PloS one - 1 Jan 2021

Song Zhipeng, Chen Lu, Pang Shuchao, Yan Bo

Abstract excerpt

BACKGROUND: Acute myocardial infarction (AMI) is a severe type of coronary artery disease, caused by coronary occlusion and followed by cardiac ischaemia. GATA binding protein 5 (GATA5) is an important member of GATA family and plays an important role in vascular inflammation, endothelial function, oxidative stress and cell metabolism. Previous studies have shown that the DNA sequence variants (DSVs) in GATA4 and...

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PMID: 33684162
DOI: 10.1371/journal.pone.0248203
PMCID: PMC7939267

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