Article
The -283C/T polymorphism of the DNMT3B gene influences the progression of joint destruction in rheumatoid arthritis.
Rheumatology international - 1 Aug 2010
Nam Eon Jeong, Kim Kyung Hoon, Han Seung Woo, Cho Chang Min, Lee Jongmin, Park Jae Yong, Kang Young Mo
Abstract excerpt
The objective of this study is to investigate the association between the -283C/T polymorphism at the promotor of DNMT3B gene and susceptibility to rheumatoid arthritis (RA) and to evaluate the effect of the polymorphism on clinical features such as progression of joint destruction in RA. A total of 309 patients with RA were compared with 297 control subjects. Genotyping of the -283C/T polymorphism was performed...
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