Article
Matrix metalloproteinase-3 gene polymorphism and its mRNA expression in rheumatoid arthritis.
Genetics and molecular research : GMR - 2 Dec 2015
Ma M J, Liu H C, Qu X Q, Wang J L
Abstract excerpt
Matrix metalloproteinase-3 (MMP-3) can mediate the occurrence and development of rheumatoid arthritis (RA). The MMP3 promoter gene exhibits polymorphism with 5A/6A alleles. We investigated the correlation between the expression of MMP3 gene polymorphism and RA to provide an objective basis for prognosis evaluation. We enrolled 80 RA patients and 80 healthy subjects. Enzyme-linked immunosorbent assay was used to...
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