Article
Genetic polymorphisms of the DNA repair gene MPG may be associated with susceptibility to rheumatoid arthritis.
Journal of applied genetics - 1 Jan 2010
Chen S Y, Wan L, Huang C M, Huang Y C, Sheu J J C, Lin Y J, Liu S P, Lan Y C, Lai C H, Lin C W, Tsai C H, Tsai F J
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic autoimmune disease and can lead to deformities and severe disabilities, due to irreversible damage of tendons, joints, and bones. A previous study indicated that a DNA repair system was involved in the development of RA. In this study, we investigated the association of four N-methylpurine-DNA glycosylase (MPG) gene polymorphisms (rs3176364, rs710079, rs2858056, and...
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