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Article

PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.

Journal of nutrigenetics and nutrigenomics - 1 Jan 2011

Alsaleh Aseel, Frost Gary S, Griffin Bruce A, Lovegrove Julie A, Jebb Susan A, Sanders Thomas A B, O'Dell Sandra D

Abstract excerpt

BACKGROUND/AIMS: The peroxisome proliferator-activated receptors (PPARs) are transcriptional regulators of lipid metabolism, activated by unsaturated fatty acids. We investigated independent and interactive effects of PPARγ2 gene PPARG Pro12Ala (rs1801282) andPPARαgene PPARA Leu162Val (rs1800206) genotypes with dietary intake of fatty acids on concentrations of plasma lipids in subjects of whom 47.5% had...

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Identifiers

PMID: 22378291
DOI: 10.1159/000336362

Genes

PPARG
PPARA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.PMID 22378291Read ↗

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