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Article

FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations.

British journal of haematology - 1 Dec 2009

Seedhouse Claire H, Pallis Monica, Grundy Martin, Shang Shili, Russell Nigel H

Abstract excerpt

FLT3-internal tandem duplication (ITD) mutations are heterogeneous with regards to length and proportion of DNA harbouring the mutation and the expression level of FLT3 also varies widely, however very little is known about the biological effects of these variables. We studied FLT3-associated biological parameters in 322 acute myeloid leukaemia samples to establish their importance. Expression of total FLT3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 19775300
DOI: 10.1111/j.1365-2141.2009.07901.x

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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