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Article

The relationship of DNA methylation with age, gender and genotype in twins and healthy controls.

PloS one - 26 Aug 2009

Boks Marco P, Derks Eske M, Weisenberger Daniel J, Strengman Erik, Janson Esther, Sommer Iris E, Kahn René S, Ophoff Roel A

Abstract excerpt

Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of epigenetic influence on human traits and disease. In addition to influences of age and gender, genetic control of DNA methylation levels has recently been described. We used whole blood genomic DNA in a twin set (23 MZ twin-pairs and 23 DZ twin-pairs, N = 92) as well as healthy controls (N = 96) to investigate heritability and...

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Identifiers

PMID: 19774229
DOI: 10.1371/journal.pone.0006767
PMCID: PMC2747671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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