Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations.

BMC medical genetics - 22 Sept 2009

Cha Seongwon, Koo Imhoi, Choi Sun Mi, Park Byung Lae, Kim Kil Soo, Kim Jae-Ryong, Shin Hyoung Doo, Kim Jong Yeol

Abstract excerpt

BACKGROUND: While INSIG2 has been reported to be associated with BMI in many populations, conflicting results have prevented consensus over its role. In analyses of mice and cell cultures the gene has been found to be involved in the regulation of cholesterol synthesis; however, no relationship has been found with cholesterol metabolism in human epidemiological research. Therefore, this study attempts to assess...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol

Share to Intracellular Signaling Peptides and Proteins

Share to Membrane Proteins

Share to Obesity

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19772594
DOI: 10.1186/1471-2350-10-96
PMCID: PMC2759923

Genes

INSIG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations.PMID 19772594Read ↗

Association of the common genetic variant upstream of INSIG2 gene with obesity related phenotypes in Chinese children and adolescents.Semantic proximity Read ↗

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.Semantic proximity Read ↗

Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays.Semantic proximity Read ↗

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women.Semantic proximity Read ↗

A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans.Semantic proximity Read ↗

INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism.Semantic proximity Read ↗

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.Semantic proximity Read ↗

No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.Semantic proximity Read ↗

INSIG2 promoter variant, obesity markers and lipid parameters - No association in a large Slavonic Caucasian population sample.Semantic proximity Read ↗

The common genetic variant upstream of INSIG2 gene is not associated with obesity in Indian population.Semantic proximity Read ↗

INSIG2 gene polymorphism is not associated with obesity in Caucasian, Afro-Caribbean and Indian subjects.Semantic proximity Read ↗

INSIG2 G-102A promoter variant exhibits context-dependent effect on HDL-cholesterol levels but not on BMI in Caucasians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.