INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

doi:10.1007/s10038-008-0317-8

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

Journal of human genetics - 1 Jan 2008

Hotta Kikuko, Nakamura Michihiro, Nakata Yoshio, Matsuo Tomoaki, Kamohara Seika, Kotani Kazuaki, Komatsu Ryoya, Itoh Naoto, Mineo Ikuo, Wada Jun, Masuzaki Hiroaki, Yoneda Masato, Nakajima Atsushi, Miyazaki Shigeru, Tokunaga Katsuto, Kawamoto Manabu, Funahashi Tohru, Hamaguchi Kazuyuki, Yamada Kentaro, Hanafusa Toshiaki, Oikawa Shinichi, Yoshimatsu Hironobu, Nakao Kazuwa, Sakata Toshiie, Matsuzawa Yuji, Tanaka Kiyoji, Kamatani Naoyuki, Nakamura Yusuke

Abstract excerpt

The single nucleotide polymorphism (SNP) rs7566605 in the upstream region of the insulin-induced gene 2 (INSIG2) is associated with the obesity phenotype in many Caucasian populations. In Japanese, this association with the obesity phenotype is not clear. To investigate the relationship between r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Frequency

Share to Genetic Linkage

Share to Intracellular Signaling Peptides and Proteins

Share to Japan

Share to Membrane Proteins

Share to Obesity, Morbid

Source

Open in PubMed Open full text

Identifiers

PMID: 18615239
DOI: 10.1007/s10038-008-0317-8
PMCID: PMC2522377

Genes

INSIG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18615239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.PMID 18615239Read ↗

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women.Semantic proximity Read ↗

Association of the common genetic variant upstream of INSIG2 gene with obesity related phenotypes in Chinese children and adolescents.Semantic proximity Read ↗

Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China.Semantic proximity Read ↗

No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.Semantic proximity Read ↗

Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays.Semantic proximity Read ↗

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.Semantic proximity Read ↗

A common polymorphism is associated with body mass index in Uyghur population.Semantic proximity Read ↗

The common genetic variant upstream of INSIG2 gene is not associated with obesity in Indian population.Semantic proximity Read ↗

Variations in the FTO gene are associated with severe obesity in the Japanese.Semantic proximity Read ↗

A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans.Semantic proximity Read ↗

Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations.Semantic proximity Read ↗

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.