No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.

doi:10.1038/oby.2007.25

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Article

No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.

Obesity (Silver Spring, Md.) - 1 Jan 2008

Tabara Yasuharu, Kawamoto Ryuichi, Osawa Haruhiko, Nakura Jun, Makino Hideichi, Miki Tetsuro, Kohara Katsuhiko

Abstract excerpt

Obesity is a complex trait reflecting numerous genetic and environmental factors. Recently, a common genetic polymorphism (rs7566605) associated with a higher BMI was found in proximity to the insulin induced protein 2 (INSIG2 ) gene, with replication in four unrelated populations living in Western countries. We investigated the susceptibility to the polymorphism amongst the general Japanese population (n =...

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Identifiers

PMID: 18223638
DOI: 10.1038/oby.2007.25

Genes

INSIG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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Related research

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Research trail→

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No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population.PMID 18223638Read ↗

No association between rs7566605 variant and being overweight in Japanese.Semantic proximity Read ↗

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.Semantic proximity Read ↗

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.Semantic proximity Read ↗

The common genetic variant upstream of INSIG2 gene is not associated with obesity in Indian population.Semantic proximity Read ↗

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women.Semantic proximity Read ↗

INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism.Semantic proximity Read ↗

Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations.Semantic proximity Read ↗

A common polymorphism is associated with body mass index in Uyghur population.Semantic proximity Read ↗

Association of the common genetic variant upstream of INSIG2 gene with obesity related phenotypes in Chinese children and adolescents.Semantic proximity Read ↗

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.Semantic proximity Read ↗

Lack of association between a common polymorphism near the INSIG2 gene and BMI, myocardial infarction, and cardiovascular risk factors.Semantic proximity Read ↗

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).Semantic proximity Read ↗

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