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Article

Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk.

Thyroid : official journal of the American Thyroid Association - 1 Oct 2009

Bastos Helder Novais, Antão Mónica Rego, Silva Susana N, Azevedo Ana Paula, Manita Isabel, Teixeira Valdemar, Pina Julieta Esperança, Gil Octávia Monteiro, Ferreira Teresa Cruz, Limbert Edward, Rueff José, Gaspar Jorge Francisco

Abstract excerpt

BACKGROUND: Ionizing radiation exposure has been pointed out as a risk factor for thyroid cancer. The double-strand breaks induced by this carcinogen are usually repaired by homologous recombination repair pathway, a pathway that includes several polymorphic genes. Since there is a scarcity of data about the involvement of these gene polymorphisms in thyroid cancer susceptibility, we carried out a case-control...

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Source

Identifiers

PMID: 19772428
DOI: 10.1089/thy.2009.0099

Genes

RAD51
XRCC3
XRCC2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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