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Article

Evidence of enhanced expression of osteopontin in spinal hyperostosis of the twy mouse.

Spine - 15 Jul 2009

Aiba Atsuomi, Nakajima Arata, Okawa Akihiko, Koda Masao, Yamazaki Masashi

Abstract excerpt

STUDY DESIGN: Gene expression and protein localization of osteopontin (OPN) in spinal hyperostosis of the twy mouse by means of in situ hybridization, immunohistochemistry, and Northern blot analysis. OBJECTIVE: To verify the involvement of OPN in spinal hyperostosis in the twy mouse and elucidate its ossification pattern at molecular levels. SUMMARY OF BACKGROUND DATA: OPN is a molecule that consistently...

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PMID: 19770606
DOI: 10.1097/BRS.0b013e3181aa01fc

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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