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Article

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

Antimicrobial agents and chemotherapy - 1 Dec 2009

Mwai Leah, Kiara Steven M, Abdirahman Abdi, Pole Lewa, Rippert Anja, Diriye Abdi, Bull Pete, Marsh Kevin, Borrmann Steffen, Nzila Alexis

Abstract excerpt

We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association with polymorphisms in pfcrt at codon 76 and pfmdr1 at codon 86, as well as with variations of the copy number of pfmdr1. The m...

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Identifiers

PMID: 19770282
DOI: 10.1128/AAC.00638-09
PMCID: PMC2786317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19770282-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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