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Article

Cholinergic switch associated with morphological differentiation in neuroblastoma.

The Journal of pathology - 1 Dec 2009

Bourdeaut Franck, Janoueix-Lerosey Isabelle, Lucchesi Carlo, Paris Régine, Ribeiro Agnès, de Pontual Loïc, Amiel Jeanne, Lyonnet Stanislas, Pierron Gaëlle, Michon Jean, Peuchmaur Michel, Delattre Olivier

Abstract excerpt

The morphology of malignant cells distinguishes between undifferentiated, poorly differentiated and differentiating neuroblastomas and constitutes a strong prognostic factor. Spontaneous or treatment-induced maturation characterizes a subset of neuroblastomas. It constitutes the basis of retinoic acid treatment to improve survival in aggressive neuroblastomas. However, the molecular events that drive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19768740
DOI: 10.1002/path.2614

Genes

DBH
GATA2
ASCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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