Article
Phenylethynylpyrene excimer forming hybridization probes for fluorescence SNP detection.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Prokhorenko Igor A, Astakhova Irina V, Momynaliev Kuvat T, Zatsepin Timofei S, Korshun Vladimir A
Abstract excerpt
Excimer formation is a unique feature of some fluorescent dyes (e.g., pyrene) which can be used for probing the proximity of biomolecules. Pyrene excimer fluorescence has previously been used for homogeneous detection of single nucleotide polymorphism (SNP) on DNA. 1-Phenylethynylpyrene (1-1-PEPy...
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