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Article

Pyrene-functionalized 2'-amino-alpha-L-LNA as potential diagnostic probes.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2007

Kumar T Santhosh, Wengel Jesper, Hrdlicka Patrick J

Abstract excerpt

Oligodeoxyribonucleotides (ONs) containing two incorporations of 2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA monomer Y are sensitive probes for detection of single nucleotide polymorphisms (SNP) in DNA. In addition, the ability of ONs containing pyrene-functionalized 2'-amino-alpha-L-LNA monomers (W-Z) to stabilize duplexes with an abasic site is demonstrated.

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PMID: 18066793
DOI: 10.1080/15257770701538908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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