Article
A novel procedure for simple and efficient genotyping of single nucleotide polymorphisms by using the Zn2+-cyclen complex.
Nucleic acids research - 15 Nov 2002
Kinoshita-Kikuta Emiko, Kinoshita Eiji, Koike Tohru
Abstract excerpt
The analysis of single nucleotide polymorphisms (SNPs) is increasingly utilized in the study of various genetic determinants. Here, we introduce a simple, rapid, low-cost and accurate procedure for the detection of SNPs by polyacrylamide gel electrophoresis (PAGE) with a novel additive, the Zn2+-...
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