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Article

Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer.

The Journal of surgical research - 1 Dec 2010

Yam Clinton, Zhao Ming, Hayashi Katsuhiro, Ma Huaiyu, Kishimoto Hiroyuki, McElroy Michele, Bouvet Michael, Hoffman Robert M

Abstract excerpt

Cancer of the exocrine pancreas is the fourth leading cause of cancer deaths in the United States. Currently, surgical resection is the only hope for cure. The majority of patients present with locally-advanced or metastatic disease. The most common site for distant metastasis is the liver. We report here a modified auxotrophic strain of S. typhimurium that can target and inhibit the growth of liver metastasis in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19766244
DOI: 10.1016/j.jss.2009.02.023
PMCID: PMC2888721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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